{"id":13796,"date":"2019-02-06T21:08:44","date_gmt":"2019-02-06T20:08:44","guid":{"rendered":"https:\/\/www.onacustica.net\/hallan-nuevas-neuronas-en-el-oido-interno-que-podria-permitir-terapias-para-trastornos-auditivos\/"},"modified":"2023-11-09T12:15:31","modified_gmt":"2023-11-09T11:15:31","slug":"hallan-nuevas-neuronas-en-el-oido-interno-que-podria-permitir-terapias-para-trastornos-auditivos","status":"publish","type":"post","link":"https:\/\/www.onacustica.net\/ca\/hallan-nuevas-neuronas-en-el-oido-interno-que-podria-permitir-terapias-para-trastornos-auditivos\/","title":{"rendered":"Troben noves neurones en l’o\u00efda interna que podria permetre ter\u00e0pies per a trastorns auditius"},"content":{"rendered":"

L’estudi mostra que aquests tres tipus de neurones probablement exerceixen un paper en la decodificaci\u00f3 de la intensitat s\u00f2nica<\/h3>\n

 <\/p>\n

Els investigadors de l’Institut Karolinska<\/a>, a Su\u00e8cia, han identificat quatre tipus de neurones en el sistema auditiu perif\u00e8ric, tres de les quals s\u00f3n noves per a la ci\u00e8ncia, cosa que podria ajudar a conduir cap a noves ter\u00e0pies per a diversos tipus de trastorns de l’audici\u00f3, com el tinnitus i la p\u00e8rdua d’audici\u00f3 relacionada amb l’edat.<\/p>\n

\u00abAra sabem que hi ha tres rutes diferents en el sistema auditiu central, en lloc de nom\u00e9s una. Aix\u00f2 ens fa estar m\u00e9s ben preparats per comprendre el paper que exerceixen les diferents neurones en l’audici\u00f3. Tamb\u00e9 hem determinat quins gens estan actius en els tipus de c\u00e8l\u00b7lules individuals\u00bb, ha declarat el l\u00edder del grup de recerca al Departament de Neuroci\u00e8ncia de l’Institut Karolinska, Fran\u00e7ois Lallemend.<\/p>\n

Quan el so arriba a l’o\u00efda interna, es converteix en senyals el\u00e8ctrics que es transmeten al cervell a trav\u00e9s de les c\u00e8l\u00b7lules nervioses de l’orella a la c\u00f2clea. Anteriorment, la majoria d’aquestes c\u00e8l\u00b7lules es consideraven de dos tipus: neurones tipus 1 i tipus 2, tipus 1 que transmetia la major part de la informaci\u00f3 auditiva.<\/p>\n

L’estudi ha demostrat que les c\u00e8l\u00b7lules tipus 1 en realitat comprenen tres tipus de c\u00e8l\u00b7lules molt diferents, la qual cosa coincideix amb investigacions anteriors que mostren variacions en les propietats el\u00e8ctriques i la resposta s\u00f2nica de les c\u00e8l\u00b7lules tipus 1.<\/p>\n

Aix\u00ed mateix, l’equip va realitzar el seu estudi en models experimentals utilitzant la t\u00e8cnica relativament nova de seq\u00fcenciaci\u00f3 d’ARN de c\u00e8l\u00b7lules individuals. El resultat \u00e9s un cat\u00e0leg dels gens expressats en les c\u00e8l\u00b7lules nervioses, que poden proporcionar als cient\u00edfics una base s\u00f2lida per comprendre millor el sistema auditiu i per idear noves ter\u00e0pies i medicaments.<\/p>\n

\u00ab<\/strong>Nue<\/strong>stro estudi pot obrir el cam\u00ed per al desenvolupament d’eines gen\u00e8tiques que es poden utilitzar per a nous tractaments per a diferents tipus de trastorns de l’audici\u00f3, com el tinnitus\u00bb, diu el doctor Lallemend.<\/strong><\/em>\u00abEl nostre mapatge tamb\u00e9 pot donar lloc a diferents formes d’influir en la funci\u00f3 de les c\u00e8l\u00b7lules nervioses individuals al cos\u00bb.<\/p>\n

L’estudi mostra que aquests tres tipus de neurones probablement exerceixen un paper en la decodificaci\u00f3 de la intensitat s\u00f2nica (\u00e9s a dir, el volum), una funci\u00f3 que \u00e9s crucial durant les converses en un entorn soroll\u00f3s, que depenen de la capacitat de filtrar el soroll de fons. Aquesta propietat tamb\u00e9 \u00e9s important en diferents formes de trastorns de l’audici\u00f3, com tinnitus o hiperac\u00fasia (hipersensibilitat al so).<\/strong><\/em><\/p>\n

\u00abUna vegada que sabem quines neurones causen hiperac\u00fasia, podrem comen\u00e7ar a investigar noves ter\u00e0pies per protegir-les o reparar-les. El seg\u00fcent pas \u00e9s mostrar quin efecte tenen aquestes c\u00e8l\u00b7lules nervioses individuals en el sistema auditiu, la qual cosa pot conduir al desenvolupament de millors ajudes auditives, com els implants coclears\u00bb, ha concl\u00f2s Lallemend.<\/p>\n

FONT: Elm\u00e9dicointeractivo.com<\/p>\n","protected":false},"excerpt":{"rendered":"

L’estudi mostra que aquests tres tipus de neurones probablement exerceixen un paper en la decodificaci\u00f3 de la intensitat s\u00f2nica   Els investigadors de l’Institut Karolinska, a Su\u00e8cia, han identificat quatre tipus de neurones en el sistema auditiu perif\u00e8ric, tres de les quals s\u00f3n noves per a la ci\u00e8ncia, cosa que podria ajudar a conduir cap […]<\/p>\n","protected":false},"author":1,"featured_media":13731,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[109],"tags":[],"class_list":["post-13796","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saber-i-oir"],"acf":[],"yoast_head":"\nTroben noves neurones en l'o\u00efda interna que podria permetre ter\u00e0pies per a trastorns auditius - Onac\u00fastica<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.onacustica.net\/ca\/hallan-nuevas-neuronas-en-el-oido-interno-que-podria-permitir-terapias-para-trastornos-auditivos\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Troben noves neurones en l'o\u00efda interna que podria permetre ter\u00e0pies per a trastorns auditius - 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